3,5-Bis(trifluoromethyl)phenylacetic Acid CAS 85068-33-3 Purity >99.0% (HPLC) Netupitant Intermediate

Short Description:

3,5-Bis(trifluoromethyl)phenylacetic Acid

CAS: 85068-33-3

Purity: ≥99.0% (HPLC)

Appearance: White or Off-White Crystalline Powder

Intermediate of Netupitant (CAS: 290297-26-6)

Contact: Dr. Alvin Huang

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E-Mail: alvin@ruifuchem.com

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Product Detail

Product Tags

85068-33-3 - Description:

Ruifu Chemical is the leading manufacturer of 3,5-Bis(trifluoromethyl)phenylacetic Acid (CAS: 85068-33-3) with high quality, intermediate of Netupitant (CAS: 290297-26-6). Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Please contact: alvin@ruifuchem.com

85068-33-3 - Chemical Properties:

Chemical Name	3,5-Bis(trifluoromethyl)phenylacetic Acid
Synonyms	2-[3,5-Di(trifluoromethyl)phenyl]acetic Acid
CAS Number	85068-33-3
Stock Status	In Stock, Production Scale Up to Hundreds of Kilograms
Molecular Formula	C10H6F6O2
Molecular Weight	272.14
Melting Point	121.0~130.0℃ (lit.)
Solubility Methanol	Soluble 25mg/mL, Clear, Colorless
COA & MSDS	Available
Place of Origin	Shanghai, China
Brand	Ruifu Chemical

85068-33-3 - Specifications:

Item	Specifications
Appearance	White or Off-White Crystalline Powder
Purity / Analysis Method	≥99.0% (HPLC)
Melting Point	121.0~130.0℃
Loss on Drying	≤1.00%
Total Impurities	≤1.00%
Fluorine NMR Spectrum	Conforms to Structure
Infrared Spectrum	Conforms to Structure
Test Standard	Enterprise Standard
Usage	Intermediate of Netupitant (CAS: 290297-26-6)

Package & Storage:

Package: Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.

Storage Condition: Store in sealed containers at cool and dry place; Protect from light and moisture.

Advantages:

FAQ:

85068-33-3 - Risk and Safety:

Hazard Symbols Xi - Irritant
Risk Codes 36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S36 - Wear suitable protective clothing.
S37/39 - Wear suitable gloves and eye/face protection
WGK Germany 3
HS Code 2916399090
Hazard Class IRRITANT

85068-33-3 - Application:

3,5-Bis(trifluoromethyl)phenylacetic Acid (CAS: 85068-33-3) is mainly used in pharmaceutical industry as a pharmaceutical intermediate. 3,5-Bis(trifluoromethyl)phenylacetic Acid can be used as an intermediate of Netupitant (CAS: 290297-26-6), chemical name 2-[3,5-bis(trifluoromethyl)phenyl]-N,2-dimethyl-N-[4-(2-methylphenyl)-6-(4-methylpiperazin-1-yl)pyridin-3-yl]propanamide. Netupitant, originally developed by Helsinn Healthcare and later licensed to Eisai, Inc., was approved in the USA in October 2014 for the treatment of chemotherapy-induced nausea and emesis.